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. 1998 Apr;52(4):272-6.
doi: 10.1136/jech.52.4.272.

Use of sequential case-control studies to investigate a community Salmonella outbreak in Wales

L J Llewellyn  1 , M R Evans, S R Palmer
Affiliations

Use of sequential case-control studies to investigate a community Salmonella outbreak in Wales

L J Llewellyn et al. J Epidemiol Community Health. 1998 Apr.

Abstract

Study objective: To establish the source of a community outbreak of Salmonella typhimurium definitive type 124.

Design: Two stage case-control study.

Setting: Three districts in south east Wales.

Subjects: Cases of salmonella food poisoning and community controls.

Main results: An initial case-control study identified an association between illness and eating ham (odds ratio 4.50, 95% confidence intervals 1.10, 21.8) and also found a possible association between illness and food bought from delicatessen stores (odds ratio 5.03, 95% confidence intervals 1.01, 32.3). However, only after a second stage case-control study was a single common ham producer identified as the source (odds ratio 25.0, 95% confidence intervals 2.33, 1155).

Conclusion: Sequential case-control studies are an important and underused tool in the investigation of community outbreaks.

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