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Clinical Trial
. 1998 Jun;36(6):1808-10.
doi: 10.1128/JCM.36.6.1808-1810.1998.

Positive result by serology indicates active Helicobacter pylori infection in patients with atrophic gastritis

A Kokkola  1 , H Rautelin, P Puolakkainen, P Sipponen, M Färkkilä, R Haapiainen, T U Kosunen
Affiliations
Clinical Trial

Positive result by serology indicates active Helicobacter pylori infection in patients with atrophic gastritis

A Kokkola et al. J Clin Microbiol. 1998 Jun.

Abstract

Patients with atrophic corpus gastritis and elevated Helicobacter pylori antibody titers but 13C-urea breath test (13C-UBT) and histology results negative for H. pylori were randomized into eradication therapy or follow-up only. Antibody levels decreased significantly in six out of seven patients in the eradication group, while in the follow-up group, the titers declined in only one out of eight patients. In patients with atrophic corpus gastritis, positive serology results may indicate an ongoing infection in spite of negative 13C-UBT and histology results.

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