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Clinical Trial
. 1998 Jun;36(6):1808-10.
doi: 10.1128/JCM.36.6.1808-1810.1998.

Positive result by serology indicates active Helicobacter pylori infection in patients with atrophic gastritis

A Kokkola  1 , H Rautelin, P Puolakkainen, P Sipponen, M Färkkilä, R Haapiainen, T U Kosunen
Affiliations
Clinical Trial

Positive result by serology indicates active Helicobacter pylori infection in patients with atrophic gastritis

A Kokkola et al. J Clin Microbiol. 1998 Jun.

Abstract

Patients with atrophic corpus gastritis and elevated Helicobacter pylori antibody titers but 13C-urea breath test (13C-UBT) and histology results negative for H. pylori were randomized into eradication therapy or follow-up only. Antibody levels decreased significantly in six out of seven patients in the eradication group, while in the follow-up group, the titers declined in only one out of eight patients. In patients with atrophic corpus gastritis, positive serology results may indicate an ongoing infection in spite of negative 13C-UBT and histology results.

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References

    1. Bell G D, Powell K U, Burridge S M, Bowden A F, Atoyebi W, Bolton G H, Jones P H, Brown C. Rapid eradication of Helicobacter pylori infection. Aliment Pharmacol Ther. 1995;9:41–46. - PubMed
    1. Borody T J, Andrews P, Jankiewicz E, Ferch N, Carroll M. Apparent reversal of early gastric mucosal atrophy after triple therapy for Helicobacter pylori. Am J Gastroenterol. 1993;88:1266–1268. - PubMed
    1. Correa P, Haenszel W, Cuello C, Zavala D, Fontham E, Zarama G, Tannenbaum S, Collazos T, Ruiz B. Gastric precancerous process in a high risk population: cohort follow-up. Cancer Res. 1990;50:4737–4740. - PubMed
    1. Forbes G M, Warren J R, Glaser M E, Cullen D J, Marshall B J, Collins B J. Long-term follow-up of gastric histology after Helicobacter pylori eradication. J Gastroenterol Hepatol. 1996;11:670–673. - PubMed
    1. Hirschl A M, Brandstätter G, Dragosics B, Hentschel E, Kundi M, Rotter M L, Schütze K, Taufer M. Kinetics of specific IgG antibodies for monitoring the effect of anti-Helicobacter pylori chemotherapy. J Infect Dis. 1993;168:763–766. - PubMed

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