The reaction between thiols and 8-azidoadenosine derivatives
- PMID: 9623
- PMCID: PMC343088
- DOI: 10.1093/nar/3.9.2331
The reaction between thiols and 8-azidoadenosine derivatives
Abstract
Thiols react at room temperature in dilute solution with 8-azidoadenosine and its nucleotides to give the corresponding 8-aminoadenosine derivatives. The reaction which takes place in the dark is base-catalysed and is particularly rapid when dithiols, e.g. dithiothreitol are used.
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