Removal of serum beta-2 microglobulin using high-performance membranes and analysis of changes in serum BMG levels after dialysis
- PMID: 9627039
- DOI: 10.1159/000013341
Removal of serum beta-2 microglobulin using high-performance membranes and analysis of changes in serum BMG levels after dialysis
Abstract
Background/aims: The present study was undertaken to analyze the beta2-microglobulin (BMG)-removing efficiency of high-performance membranes (HPMs) in relation to changes in serum BMG levels after dialysis.
Methods: In 10 stable dialysis patients, six different HPMs were used in a crossover method. Serum BMG levels were measured immediately before dialysis, immediately after, 4 h after, and immediately before the next dialysis. On the basis of these measurements, the BMG removal rate was calculated.
Results: The BMG removal rate as calculated on the basis of the BMG level immediately after dialysis was 11.29% higher than the rate calculated on the basis of the BMG level 4 h after dialysis.
Conclusion: The BMG removal rate can be overestimated if it is calculated on the basis of the BMG level immediately after dialysis.
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