doi: 10.1016/s0171-9335(98)80069-1.
PDGF and TGF-beta induce cell shape changes in invertebrate immunocytes via specific cell surface receptors
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- PMID: 9628322
- DOI: 10.1016/s0171-9335(98)80069-1
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PDGF and TGF-beta induce cell shape changes in invertebrate immunocytes via specific cell surface receptors
Eur J Cell Biol.
1998 Apr.
Abstract
The presence of PDGF receptor-alpha- and -beta- and TGF-beta-receptor (type II)-like molecules on the plasma membranes of the immunocytes of the mollusc Mytilus galloprovincialis was demonstrated by an immunocytochemical procedure. Furthermore, the present study provides evidence that PDGF-AB and TGF-beta1 provoke cell shape changes in immunocytes via interactions with the respective receptors and that these extracellular signals are transduced along the phosphoinositide signaling pathway.
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