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. 1976 Jul 1;157(1):267-70.
doi: 10.1042/bj1570267.

Types I and II collagens in intervertebral disc. Interchanging radial distributions in annulus fibrosus

D R Eyre, H Muir

Types I and II collagens in intervertebral disc. Interchanging radial distributions in annulus fibrosus

D R Eyre et al. Biochem J. .

Abstract

Intervertebral disc is a highly specialized cartilaginous tissue, containing two genetic types of collagen (I and II). Analysis of peptides from a CNBr digest of collagen showed that the proportions of I and II varied gradually and inversely across pig annulus fibrosus, with exclusively type I at the extreme outer edge and exclusively type II in the nucleus pulposus.

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