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Comparative Study
. 1976 Aug 1;157(2):353-6.
doi: 10.1042/bj1570353.

Comparative activity of arylsulphatases A and B on two synthetic substrates

E E Delvin, A Pottier, F Glorieux
Comparative Study

Comparative activity of arylsulphatases A and B on two synthetic substrates

E E Delvin et al. Biochem J. .

Abstract

Rat liver and human skin fibroblasts arylsulphatase A and B activities on both 4-methylumbelliferyl sulphate and 4-nitrocatechol sulphate were compared. The intracellular distribution of activity differed markedly when 4-methylumbelliferyl sulphate was used from that observed with 4-nitrocatechol sulphate. No discrimination between control and metachromatic leucodystrophy or mucopolysaccharidosis (type VI) could be achieved when 4-methylumbelliferyl sulphate was used as substrate. These results contrast sharply with those obtained with 4-nitrocatechol sulphate and cast doubt on the validity of 4-methylumbelliferyl sulphate as substrate for the determination of arylsulphatase A and B activities.

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References

    1. Biochem Biophys Res Commun. 1975 Jan 2;64(3):955-62 - PubMed
    1. Pediatr Res. 1975 May;9(5):475-80 - PubMed
    1. Biochem Biophys Res Commun. 1974 Dec 23;61(4):1450-7 - PubMed
    1. J Neurochem. 1973 Aug;21(2):459-71 - PubMed
    1. J Neurochem. 1969 Jul;16(7):1147-55 - PubMed

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