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. 1976 Aug 1;157(2):517-20.
doi: 10.1042/bj1570517.

Isolation of (copper, zinc)-thioneins from the livers of copper-injected rats

I Bremner, B W Young

Isolation of (copper, zinc)-thioneins from the livers of copper-injected rats

I Bremner et al. Biochem J. .

Abstract

The mixed copper- and zinc-binding proteins, with mol.wt. of approx. 12000, induced in rat liver after injection of copper were isolated and characterized as metallothioneins. Three separate forms were obtained, with 7-11% total metal in the protein, equivalent to 2.6-1.6 cysteine residues/metal atom.

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