Acute inhalation toxicity of cotton plant dusts
- PMID: 963002
- PMCID: PMC1008131
- DOI: 10.1136/oem.33.3.175
Acute inhalation toxicity of cotton plant dusts
Abstract
The number of free lung-cells was studied in guinea-pigs after acute exposure to extracts of various cotton dusts. A good correlation was found between the increase in number of leucocytes in the airways and the number of Gram-negative bacteria in the different dusts. Experiments using the Shwartzmann reaction and the Limulus titration test demonstrated a relationship between the content of different endotoxins in the dusts and the pulmonary reaction. A model for the acute exposure effects after exposure to cotton dust is proposed.
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