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Review
. 1998 May;26(2):141-8.
doi: 10.1111/j.1442-9071.1998.tb01530.x.

Overview of studies on metabolic and vascular regulatory changes in early diabetic retinopathy

V A Alder  1 , E N Su, D Y Yu, S Cringle, P Yu
Affiliations
Review

Overview of studies on metabolic and vascular regulatory changes in early diabetic retinopathy

V A Alder et al. Aust N Z J Ophthalmol. 1998 May.

Erratum in

  • Aust N Z J Ophthalmol 1998 Aug;26(3):267

Abstract

The present review provides an overview of recent research describing functional changes to the retinal vasculature in very early diabetes. The research focuses on the streptozotocin rat model after 4-6 weeks of induced diabetes and describes functional changes to retinal blood flow, vascular control and retinal oxygenation, as well as a strong vasodilatory response to insulin in the retinal vasculature. The review raises the question of whether choroid dysfunction is also a feature of diabetic retinopathy.

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