Beta-blocker therapy of severe congestive heart failure in infants with left to right shunts
- PMID: 9631979
- DOI: 10.1016/s0002-9149(98)00175-1
Beta-blocker therapy of severe congestive heart failure in infants with left to right shunts
Abstract
We report on the clinical and neurohumoral effects of adding low-dose propranolol to conventional therapy with digoxin and diuretics in 6 infants with severe congestive heart failure due to large left-to-right shunts. A significant decrease in heart failure scores and a decrease of the highly activated renin-angiotensin-1 aldosterone system by approximately 70% strongly suggests a beneficial effect of this new therapeutic approach.
Similar articles
-
Should beta-blockers be used for the treatment of pediatric patients with chronic heart failure?Paediatr Drugs. 2002;4(12):771-8. doi: 10.2165/00128072-200204120-00001. Paediatr Drugs. 2002. PMID: 12431129 Review.
-
Propranolol treatment of congestive heart failure in infants with congenital heart disease: The CHF-PRO-INFANT Trial. Congestive heart failure in infants treated with propanol.Int J Cardiol. 2001 Jul;79(2-3):167-73. doi: 10.1016/s0167-5273(01)00413-2. Int J Cardiol. 2001. PMID: 11461738 Clinical Trial.
-
Effectiveness of low dose captopril versus propranolol therapy in infants with severe congestive failure due to left-to-right shunts.Int J Cardiol. 2000 Nov-Dec;76(2-3):227-33. doi: 10.1016/s0167-5273(00)00384-3. Int J Cardiol. 2000. PMID: 11104878
-
Effects of therapeutic beta blockade on myocardial function and cardiac remodelling in congenital cardiac disease.Cardiol Young. 2003 Feb;13(1):36-43. doi: 10.1017/s1047951103000076. Cardiol Young. 2003. PMID: 12691286 Clinical Trial.
-
Beta-adrenergic blocking agents in the treatment of congestive heart failure: mechanisms and clinical results.Annu Rev Med. 1997;48:103-14. doi: 10.1146/annurev.med.48.1.103. Annu Rev Med. 1997. PMID: 9046949 Review.
Cited by
-
Role of β-blocker therapy in pediatric heart failure.Ped Health. 2010;4(1):45-58. doi: 10.2217/phe.09.65. Ped Health. 2010. PMID: 21799703 Free PMC article.
-
Pediatric heart failure therapy with beta-adrenoceptor antagonists.Paediatr Drugs. 2008;10(2):125-34. doi: 10.2165/00148581-200810020-00007. Paediatr Drugs. 2008. PMID: 18345722 Review.
-
Prospective single-arm protocol of carvedilol in children with ventricular dysfunction.Pediatr Cardiol. 2006 May-Jun;27(3):336-42. doi: 10.1007/s00246-005-1159-1. Pediatr Cardiol. 2006. PMID: 16596434
-
Beta-blockers for congestive heart failure in children.Cochrane Database Syst Rev. 2020 Jul 23;7(7):CD007037. doi: 10.1002/14651858.CD007037.pub4. Cochrane Database Syst Rev. 2020. PMID: 32700759 Free PMC article.
-
Should beta-blockers be used for the treatment of pediatric patients with chronic heart failure?Paediatr Drugs. 2002;4(12):771-8. doi: 10.2165/00128072-200204120-00001. Paediatr Drugs. 2002. PMID: 12431129 Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical