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. 1998 Jun 1;81(11):1366-8.
doi: 10.1016/s0002-9149(98)00175-1.

Beta-blocker therapy of severe congestive heart failure in infants with left to right shunts

R Buchhorn  1 , D Bartmus, W Siekmeyer, M Hulpke-Wette, R Schulz, J Bürsch
Affiliations

Beta-blocker therapy of severe congestive heart failure in infants with left to right shunts

R Buchhorn et al. Am J Cardiol. .

Abstract

We report on the clinical and neurohumoral effects of adding low-dose propranolol to conventional therapy with digoxin and diuretics in 6 infants with severe congestive heart failure due to large left-to-right shunts. A significant decrease in heart failure scores and a decrease of the highly activated renin-angiotensin-1 aldosterone system by approximately 70% strongly suggests a beneficial effect of this new therapeutic approach.

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