Review
doi: 10.1016/s0952-7915(98)80162-3.
Long-lived plasma cells: a mechanism for maintaining persistent antibody production
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- PMID: 9638360
- DOI: 10.1016/s0952-7915(98)80162-3
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Review
Long-lived plasma cells: a mechanism for maintaining persistent antibody production
Curr Opin Immunol.
1998 Jun.
Abstract
Current models suggest that continuous antigenic stimulation of memory B cells is required to maintain long-term antibody production. In view of recent developments concerning plasma cell longevity, a new model is described that incorporates the important role of long-lived plasma cells in sustaining persistent antibody responses.
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