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Clinical Trial
. 1978 Apr 14;57(1):1-4.
doi: 10.1007/BF00426949.

Effects of perphenazine enanthate injections on prolactin levels in plasma from schizophrenic women and men

H Lindholm, B Gullberg, A Ohman, G Sedvall
Clinical Trial

Effects of perphenazine enanthate injections on prolactin levels in plasma from schizophrenic women and men

H Lindholm et al. Psychopharmacology (Berl). .

Abstract

Levels of prolactin (PRL) in plasma were determined in schizophrenic women and men after i.m. injections of 50-150 mg perphenazine enanthate (PE). In both sexes PRL levels increased dose-dependently. In men the effect was significant for 2 and in women for 9 days. Biperiden treatment did not influence the effect of PE on the PRL levels. The data support the view that clinically used doses of PE induce a small but significant blockade of central dopamine receptors.

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