Review
doi: 10.1016/s0079-6107(97)00022-9.
Structure and function of molybdopterin containing enzymes
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- PMID: 9652170
- DOI: 10.1016/s0079-6107(97)00022-9
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Review
Structure and function of molybdopterin containing enzymes
Prog Biophys Mol Biol.
1997.
Abstract
Molybdopterin containing enzymes are present in a wide range of living systems and have been known for several decades. However, only in the past two years have the first crystal structures been reported for this type of enzyme. This has represented a major breakthrough in this field. The enzymes share common structural features, but reveal different polypeptide folding topologies. In this review we give an account of the related spectroscopic information and the crystallographic results, with emphasis on structure-function studies.
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