Compartment boundaries: where, why and how?
- PMID: 9654014
Compartment boundaries: where, why and how?
Abstract
In the 1960's, Garcia Bellido and colleagues uncovered the existence of developmental compartments in Drosophila. This observation has had a lasting impact on our understanding of developmental mechanisms in flies and vertebrates. Here, I review the work that demonstrated the existence of compartments. I then conjecture on why compartments exist and review the roles of various gene products in the maintenance of compartment boundaries.
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