Review
Interactions between Wingless and Notch during the assignment of cell fates in Drosophila
Affiliations
- PMID: 9654016
Item in Clipboard
Review
Interactions between Wingless and Notch during the assignment of cell fates in Drosophila
Int J Dev Biol.
1998.
Abstract
A large number of observations suggest that, during Drosophila development there are close functional interactions between the activity of Notch receptor and that of a signaling molecule encoded by wingless gene. In this essay, I summarize these interactions and discuss the possibility that Wingless acts as a ligand for Notch as part of a switch that is iteratively involved in the assignation of cell fates during development.
Similar articles
-
Wingless modulates the effects of dominant negative notch molecules in the developing wing of Drosophila.Dev Biol. 1999 Dec 1;216(1):210-29. doi: 10.1006/dbio.1999.9502. Dev Biol. 1999. PMID: 10588873
-
Notch and wingless regulate expression of cuticle patterning genes.Mol Cell Biol. 1999 Aug;19(8):5743-58. doi: 10.1128/MCB.19.8.5743. Mol Cell Biol. 1999. PMID: 10409762 Free PMC article.
-
Notch is required for wingless signaling in the epidermis of Drosophila.Cell. 1994 Oct 21;79(2):259-72. doi: 10.1016/0092-8674(94)90195-3. Cell. 1994. PMID: 7954794
-
Formation of morphogen gradients in the Drosophila wing.Semin Cell Dev Biol. 1999 Jun;10(3):335-44. doi: 10.1006/scdb.1999.0293. Semin Cell Dev Biol. 1999. PMID: 10441548 Review.
-
Notch and Wingless signals collide.Science. 1996 Mar 29;271(5257):1822-3. doi: 10.1126/science.271.5257.1822. Science. 1996. PMID: 8596948 Review. No abstract available.
Cited by
-
The notch intracellular domain can function as a coactivator for LEF-1.Mol Cell Biol. 2001 Nov;21(22):7537-44. doi: 10.1128/MCB.21.22.7537-7544.2001. Mol Cell Biol. 2001. PMID: 11604490 Free PMC article.
-
Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine.Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6309-14. doi: 10.1073/pnas.0900427106. Epub 2009 Feb 27. Proc Natl Acad Sci U S A. 2009. PMID: 19251639 Free PMC article.
-
Engrailed-1 negatively regulates beta-catenin transcriptional activity by destabilizing beta-catenin via a glycogen synthase kinase-3beta-independent pathway.Mol Biol Cell. 2006 Jun;17(6):2572-80. doi: 10.1091/mbc.e06-01-0052. Epub 2006 Mar 29. Mol Biol Cell. 2006. PMID: 16571670 Free PMC article.
-
Loss of adenomatous polyposis coli gene function disrupts thymic development.Nat Immunol. 2005 Aug;6(8):800-9. doi: 10.1038/ni1228. Epub 2005 Jul 17. Nat Immunol. 2005. PMID: 16025118 Free PMC article.
-
The intracellular form of notch blocks transforming growth factor beta-mediated growth arrest in Mv1Lu epithelial cells.Mol Cell Biol. 2003 Sep;23(18):6694-701. doi: 10.1128/MCB.23.18.6694-6701.2003. Mol Cell Biol. 2003. PMID: 12944493 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Molecular Biology Databases