Molecular cloning of a gene encoding phospholipase D from the pathogenic and dimorphic fungus, Candida albicans
- PMID: 9655935
- DOI: 10.1016/s0167-4781(98)00067-0
Molecular cloning of a gene encoding phospholipase D from the pathogenic and dimorphic fungus, Candida albicans
Abstract
A phospholipase D gene (CaPLD) has been cloned from the Candida albicans genomic DNA library. The CaPLD is a member of a highly conserved gene family of PLD and has the highest homology to Saccharomyces cerevisiae PLD (SPO14) with an overall homology of 42%. Phylogenetic analysis indicated that fungus PLDs including CaPLD composed one of the three clusters of PLD genes.
Similar articles
-
[Molecular cloning of Candida albicans phospholipase D].Nihon Ishinkin Gakkai Zasshi. 1998;39(2):79-83. doi: 10.3314/jjmm.39.79. Nihon Ishinkin Gakkai Zasshi. 1998. PMID: 9580032 Review. Japanese.
-
Genetic characterization of a phospholipase C gene from Candida albicans: presence of homologous sequences in Candida species other than Candida albicans.Microbiology (Reading). 1998 Jan;144 ( Pt 1):55-72. doi: 10.1099/00221287-144-1-55. Microbiology (Reading). 1998. PMID: 9467900
-
Identification of the gene encoding DNA topoisomerase I from Candida albicans.FEMS Microbiol Lett. 1996 May 1;138(2-3):113-21. doi: 10.1111/j.1574-6968.1996.tb08143.x. FEMS Microbiol Lett. 1996. PMID: 9026437
-
Cloning and characterization of a gene (LIP1) which encodes a lipase from the pathogenic yeast Candida albicans.Microbiology (Reading). 1997 Feb;143 ( Pt 2):331-340. doi: 10.1099/00221287-143-2-331. Microbiology (Reading). 1997. PMID: 9043110
-
Phospholipase D structure and regulation.Chem Phys Lipids. 1999 Apr;98(1-2):127-40. doi: 10.1016/s0009-3084(99)00025-0. Chem Phys Lipids. 1999. PMID: 10358935 Review.
Cited by
-
Phospholipase D controls Dictyostelium development by regulating G protein signaling.Cell Signal. 2011 Feb;23(2):335-43. doi: 10.1016/j.cellsig.2010.09.017. Epub 2010 Oct 13. Cell Signal. 2011. PMID: 20950684 Free PMC article.
-
Phospholipase D: enzymology, functionality, and chemical modulation.Chem Rev. 2011 Oct 12;111(10):6064-119. doi: 10.1021/cr200296t. Epub 2011 Sep 22. Chem Rev. 2011. PMID: 21936578 Free PMC article. Review. No abstract available.
-
Lipolytic enzymes involved in the virulence of human pathogenic fungi.Mycobiology. 2013 Jun;41(2):67-72. doi: 10.5941/MYCO.2013.41.2.67. Epub 2013 Jun 30. Mycobiology. 2013. PMID: 23874127 Free PMC article.
-
Phospholipase D: molecular and cell biology of a novel gene family.Biochem J. 2000 Feb 1;345 Pt 3(Pt 3):401-15. Biochem J. 2000. PMID: 10642495 Free PMC article. Review.
-
Disruption of the phospholipase D gene attenuates the virulence of Aspergillus fumigatus.Infect Immun. 2012 Jan;80(1):429-40. doi: 10.1128/IAI.05830-11. Epub 2011 Nov 14. Infect Immun. 2012. PMID: 22083709 Free PMC article.
Publication types
MeSH terms
Substances
Associated data
- Actions
LinkOut - more resources
Full Text Sources
Molecular Biology Databases