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Case Reports
. 1998 May;51(4):380-2.

[Pyelocaliceal urothelial carcinoma associated with pelvis lithiasis]

[Article in Spanish]
M Medina Pérez  1 , I Valpuesta Fernández, J Valero Puerta
Affiliations
  • PMID: 9656562
Case Reports

[Pyelocaliceal urothelial carcinoma associated with pelvis lithiasis]

[Article in Spanish]
M Medina Pérez et al. Arch Esp Urol. 1998 May.

Abstract

Objective: Epithelial neoplasms of the upper collecting system account for less than 5 percent of all urothelial tumors and they are not histologically unlike those of the bladder. We report a case of pelviocaliceal urothelial carcinoma associated with a calculus in the renal pelvis.

Methods: A 75-year-old man who presented with hematuria, fever and flank pain is described. The US and CT findings disclosed a calculus in the left renal pelvis and hydronephrosis nephrectomy was performed.

Results: The pathological analysis revealed a pelviocaliceal urothelial carcinoma on an underlying stone and overexpression of the p53 protein.

Conclusion: Diagnostic imaging techniques may fail to detect tumors of the renal pelvis with a large underlying stone. The overexpression of the p53 protein may be involved in the malignant transformation of the urothelial cells.

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