Reduction of cyclosporine-induced gingival overgrowth following a change to tacrolimus. A case history involving a liver transplant patient
- PMID: 9660343
- DOI: 10.1902/jop.1998.69.6.729
Reduction of cyclosporine-induced gingival overgrowth following a change to tacrolimus. A case history involving a liver transplant patient
Erratum in
- J Periodontol 1998 Oct;69(10):1181
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Clarification.J Periodontol. 1998 Oct;69(10):1181. doi: 10.1902/jop.1998.69.10.1181a. J Periodontol. 1998. PMID: 29539816 No abstract available.
Abstract
During immunosuppression with cyclosporine, gingival overgrowth, a minor secondary effect, may appear in the first weeks of treatment. In certain cases it may affect the function and/or esthetic appearance in a manner intolerable to the patient. A new immunnosuppressive molecule, tacrolimus, presently used as a treatment of second choice to control acute corticoresistant rejection, may bring oral comfort to these patients, since it reduces gingival overgrowth to negligible levels.
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