Comparative Study
doi: 10.3109/00498257809060949.
The metabolism of S-carboxymethylcysteine in rodents, marmosets and humans
- PMID: 96615
- DOI: 10.3109/00498257809060949
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Comparative Study
The metabolism of S-carboxymethylcysteine in rodents, marmosets and humans
Xenobiotica.
1978 May.
Abstract
1. The metabolism of S-carboxymethylcysteine (Mucodyne) has been studied in the rat, rabbit, guinea-pig, marmoset and human. All species studied, except the rabbit, excrete large amounts of the parent compound. 2. Rabbits and humans give S-carboxymethylcysteine sulphoxide, rats form N-acetyl-S-carboxymethylcysteine while marmosets excrete methylmercapturic acid as other major metabolites. Traces of methylmercapturic acid sulphoxide, methylcysteine, methylcysteine sulphoxide and 3-(S-carboxymethylthio)lactic acid were also found.
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