Myocardial contrast echocardiography in the evaluation of viable myocardium after acute myocardial infarction

Abstract

Successfully reopening the infarct-related artery after acute myocardial infarction (MI) is currently achieved more frequently than before due to efficient therapeutic strategies, including new thrombolytic drugs and percutaneous transluminal coronary angioplasty. Successful reopening does not necessarily mean reperfusion; in fact the "no-reflow" phenomenon can occur. This phenomenon is due to functional and anatomic alterations, including microcirculation. Experimental and clinical studies have demonstrated that microvascular integrity is a fundamental prerequisite for ensuring viability after an acute MI. Often, studies have also shown that myocardial contrast echocardiography is a technique capable of detecting functional and anatomic conditions of microcirculation after ischemic reperfusion, and thus myocardial contrast echocardiography can be used for viability detection after acute MI.