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Case Reports
. 1998 Jul;28(7):492-6.
doi: 10.1007/s002470050393.

Upper airway obstruction and pulmonary abnormalities due to lymphoproliferative disease following bone marrow transplantation in children

B D Fletcher  1 , H E Heslop, S C Kaste, S Bodner
Affiliations
Case Reports

Upper airway obstruction and pulmonary abnormalities due to lymphoproliferative disease following bone marrow transplantation in children

B D Fletcher et al. Pediatr Radiol. 1998 Jul.

Abstract

We report three patients who developed severe supraglottic airway obstruction due to Epstein-Barr virus lymphoproliferative disease following allogeneic bone marrow transplantation. In addition to enlarged pharyngeal lymphoid tissue seen in all three patients, two had supraglottic airway narrowing and two developed pulmonary lymphoproliferative disease. They were treated with unmanipulated T cells or EBV-specific cytotoxic T lymphocytes. Life-threatening upper airway obstruction is a radiologically detectable complication of allogeneic bone marrow transplantation in children.

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  • Cytotoxic T cells and immunotherapy.
    Kitchingman GR, Rooney C. Kitchingman GR, et al. Pediatr Radiol. 1998 Jul;28(7):489-91. doi: 10.1007/s002470050392. Pediatr Radiol. 1998. PMID: 9662564 Review.

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