Fluctuation and relaxation analysis of monazomycin-induced conductance in black lipid membranes
- PMID: 966263
- DOI: 10.1007/BF01869145
Fluctuation and relaxation analysis of monazomycin-induced conductance in black lipid membranes
Abstract
Fluctuation and relaxation analyses were performed on monazomycin-induced conductance of lipid bilayer membranes. With both methods a slow (sec) and a fast (msec) current component are apparent; however, the amplitude of the slow, voltage-dependent process is greater than that of the fast component in the step relaxation experiment and less in the fluctuation experiment. The fluctuation analysis showed principally a rapid voltage-dependent process which appears to be related to the multistate character of the conducting channel. The experimental results are interpreted in terms of a simplified kinetic model which is used to calculate relaxation and noise amplitudes.
Similar articles
-
Single channel conductance at lipid bilayer membranes in presence of monazomycin.Biochim Biophys Acta. 1976 Mar 19;426(3):447-50. doi: 10.1016/0005-2736(76)90389-8. Biochim Biophys Acta. 1976. PMID: 57800 No abstract available.
-
Charge-pulse relaxation studies with lipid bilayer membranes modified by alamethicin.Biochim Biophys Acta. 1978 Feb 21;507(2):262-70. doi: 10.1016/0005-2736(78)90421-2. Biochim Biophys Acta. 1978. PMID: 626734
-
Molecular aspects of electrical excitation in lipid bilayers and cell membranes.Horiz Biochem Biophys. 1976;2:230-84. Horiz Biochem Biophys. 1976. PMID: 776770 Review.
-
The effect of lanthanum on alamethicin channels in black lipid bilayers.Biochim Biophys Acta. 1981 Jan 8;640(1):185-94. doi: 10.1016/0005-2736(81)90544-7. Biochim Biophys Acta. 1981. PMID: 6260169
-
Planar lipid bilayer membranes.Methods Enzymol. 1974;32:513-39. Methods Enzymol. 1974. PMID: 4614005 Review. No abstract available.
Cited by
-
Alamethicin-induced conductances in lipid bilayers: I. Data analysis and simple steady-state model.J Membr Biol. 1980 Jun 30;55(1):9-27. doi: 10.1007/BF01926367. J Membr Biol. 1980. PMID: 7401170
-
Electrical noise from lipid bilayer membranes in the presence of hydrophobic ions.J Membr Biol. 1977 Dec 15;37(3-4):321-45. doi: 10.1007/BF01940938. J Membr Biol. 1977. PMID: 599554
-
Acetylcholine receptor kinetics.J Membr Biol. 1981 Feb 28;58(3):161-74. doi: 10.1007/BF01870902. J Membr Biol. 1981. PMID: 6260951 Review. No abstract available.
-
Decamethonium both opens and blocks endplate channels.Proc Natl Acad Sci U S A. 1978 Jun;75(6):2994-8. doi: 10.1073/pnas.75.6.2994. Proc Natl Acad Sci U S A. 1978. PMID: 307251 Free PMC article.
-
Conductance noise of monazomycin-doped bilayer membranes.J Membr Biol. 1979 Apr 9;45(3-4):277-92. doi: 10.1007/BF01869289. J Membr Biol. 1979. PMID: 458843