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. 1976 Jun 30;27(4):381-91.
doi: 10.1007/BF01869147.

Effect of transepithelial concentration gradients on the passive fluxes of sodium across toad bladder

J S Chen, M Walser

Effect of transepithelial concentration gradients on the passive fluxes of sodium across toad bladder

J S Chen et al. J Membr Biol. .

Abstract

Bidirectional sodium fluxes across toad bladder were measured after eliminating active transport with ouabain. Mucosal sodium concentration, Cm, was progressively reduced (from 114 to 3 mM) while serosal sodium remained constant. Potential difference was maintained at zero by current passage. The ratio, Q, of the bulk permeability coefficient for sodium, P, to the tracer sodium permeability coefficient, P, was found to remain constant as Cm decreased. Equations were derived on this basis for bidirectional fluxes and for P and P as functions of Cm, which corresponded closely to the observed data. The explanation for the observed value of Q and its constancy under these conditions is uncertain.

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References

    1. J Membr Biol. 1974;19(1):93-104 - PubMed
    1. J Membr Biol. 1975;20(1-2):191-204 - PubMed
    1. J Membr Biol. 1975 Apr 23;21(1-2):87-98 - PubMed
    1. J Membr Biol. 1974;18(3-4):365-78 - PubMed
    1. Biophys J. 1969 Aug;9(8):1006-28 - PubMed

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