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Review
. 1998 Jun;27(2):465-83.
doi: 10.1016/s0889-8529(05)70017-7.

The science and therapy of glucocorticoid-induced bone loss

N E Lane  1 , B Lukert
Affiliations
Review

The science and therapy of glucocorticoid-induced bone loss

N E Lane et al. Endocrinol Metab Clin North Am. 1998 Jun.

Abstract

Glucocorticoids are critical in the management of chronic, noninfectious, inflammatory diseases. Bone loss is a most devastating side effect of these powerful medications. Glucocorticoids produce bone loss by altering calcium metabolism, suppressing gonadal hormone production, and inhibiting bone formation. Now that the mechanism of glucocorticoid-induced bone loss is understood and effective medications are available, this disease can be prevented and reversed.

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