Rolling hairpin model for replication of parvovirus and linear chromosomal DNA
- PMID: 967244
- DOI: 10.1038/263106a0
Rolling hairpin model for replication of parvovirus and linear chromosomal DNA
Abstract
A novel, quasicircular scheme is proposed for the replication of parvovirus DNA. Daughter strands are initiated after the copying and rearrangement of a terminal palindromic sequence, a process termed 'hairpin transfer'. Such a process may be involved in the replication of other viruses and host cell DNA.
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