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Review
. 1998 Jun;28(3):410-3.
doi: 10.1111/j.1445-5994.1998.tb01976.x.

The role of ifosfamide in paediatric cancer

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Review

The role of ifosfamide in paediatric cancer

S H Advani. Aust N Z J Med. 1998 Jun.

Abstract

Ifosfamide is an active drug in the therapy of paediatric tumours such as rhabdomyosarcoma, Ewings' sarcoma, Wilms' tumour, neuroblastoma, germ cell tumours and lymphomas. Myelosuppression is the major toxicity along with haemorrhagic cystitis. The latter is largely prevented by the use of concomitant mesna.

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