Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1998 Jun 18;402(1-2):41-50.
doi: 10.1016/s0027-5107(97)00280-7.

Multiple antimutagenesis mechanisms affect mutagenic activity and specificity of the base analog 6-N-hydroxylaminopurine in bacteria and yeast

S G Kozmin  1 , R M Schaaper, P V Shcherbakova, V N Kulikov, V N Noskov, M L Guetsova, V V Alenin, I B Rogozin, K S Makarova, Y I Pavlov
Affiliations
Review

Multiple antimutagenesis mechanisms affect mutagenic activity and specificity of the base analog 6-N-hydroxylaminopurine in bacteria and yeast

S G Kozmin et al. Mutat Res. .

Abstract

Base analog 6-N-hydroxylaminopurine is a potent mutagen in variety of prokaryotic and eukaryotic organisms. In the review, we discuss recent results of the studies of HAP mutagenic activity, genetic control and specificity in bacteria and yeast with the emphasis to the mechanisms protecting living cells from mutagenic and toxic effects of this base analog.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources