doi: 10.1016/s0005-2736(98)00062-5.
Evidence for three-dimensional interlayer correlations in cationic lipid-DNA complexes as observed by cryo-electron microscopy
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- PMID: 9675338
- DOI: 10.1016/s0005-2736(98)00062-5
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Evidence for three-dimensional interlayer correlations in cationic lipid-DNA complexes as observed by cryo-electron microscopy
Biochim Biophys Acta.
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Free article
Abstract
A fingerprint-like pattern across multilamellar, lipid-DNA complexes is attributed to DNA condensed as parallel helices between lipid bilayers. It is argued that the patterning indicates the existence of 3-D correlation forces between DNA-covered bilayers, following the DNA-driven formation of multilamellar liposomes from unilamellar vesicles.
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