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. 1998 Jul 17;1372(2):379-83.
doi: 10.1016/s0005-2736(98)00062-5.

Evidence for three-dimensional interlayer correlations in cationic lipid-DNA complexes as observed by cryo-electron microscopy

B J Battersby  1 , R Grimm, S Huebner, G Cevc
Affiliations
Free article

Evidence for three-dimensional interlayer correlations in cationic lipid-DNA complexes as observed by cryo-electron microscopy

B J Battersby et al. Biochim Biophys Acta. .
Free article

Abstract

A fingerprint-like pattern across multilamellar, lipid-DNA complexes is attributed to DNA condensed as parallel helices between lipid bilayers. It is argued that the patterning indicates the existence of 3-D correlation forces between DNA-covered bilayers, following the DNA-driven formation of multilamellar liposomes from unilamellar vesicles.

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