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Review
. 1998;19(4):211-5.

[Intravascular malignant B-cell lymphomatosis with renal glomerular involvement: a case]

[Article in French]
C Charasse  1 , R Boulahrouz, S Le Moal, J Bousser, A Pasquiou, P Le Cacheux, K S Ang, P Simon, M P Ramée
Affiliations
  • PMID: 9675761
Review

[Intravascular malignant B-cell lymphomatosis with renal glomerular involvement: a case]

[Article in French]
C Charasse et al. Nephrologie. 1998.

Abstract

We report a case of intravascular malignant lymphomatosis observed in a 71 year-old male and characterised by the presence of a proteinuria in relation to the specific intraglomerular localisation. This malignant lymphoma, usually of the B phenotype, is rare and affects predominantly the central nervous system and the skin. Neoplastic cells home selectively to endothelium. Histological renal infiltration is frequent but a glomerular localisation, with proteinuria, is rare. The mechanism whereby lymphocytes home to endothelium cells is unclear but it could be related to the expression of lymphocyte-endothelium adhesion molecules. When present the nephrotic syndrome is associated with minimal change disease.

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