Review
doi: 10.1016/s0966-842x(98)01249-9.
Chemokine receptors and the clinical course of HIV-1 infection
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- PMID: 9675802
- DOI: 10.1016/s0966-842x(98)01249-9
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Review
Chemokine receptors and the clinical course of HIV-1 infection
Trends Microbiol.
1998 Jun.
Abstract
For several years, the cellular basis behind the differences in HIV-1 tropism and the species specificity of HIV-1 has remained unclear. Since the discovery that chemokine receptors are essential cofactors for entry of HIV-1 into cells, tremendous progress has been made in the understanding of the role played by co-receptors in HIV-1 biological variability, HIV-1 transmission and AIDS pathogenesis.
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