Corneoscleral epithelial cysts: evidence of developmental etiology

Abstract

Purpose: To describe the clinical features, histopathology, surgical management and possible etiopathogenesis of corneoscleral epithelial cysts.

Methods: Three patients with corneoscleral epithelial cysts underwent surgical ablation of the cysts. Material obtained during surgery was subjected to histopathologic analysis.

Results: At last follow-up (mean, 6.3 months), none of the cysts had recurred. All patients had improved visual acuity. Histopathology revealed the occurrence of glandular elements suggestive of lacrimal tissue in one of the cysts.

Conclusion: The presence of ectopic lacrimal tissue suggests a developmental etiology for such cysts. Marsupialization of the scleral portion of the cyst and chemical ablation of the lining epithelium of the corneal cyst with 20% trichloroacetic acid appears to be a safe and effective technique in the surgical management of corneoscleral epithelial cysts.