[The role of polyol pathways in formation of diabetic cataracts]
- PMID: 9685789
[The role of polyol pathways in formation of diabetic cataracts]
Abstract
The authors present current knowledge concerning the role of polyols in the formation of cataract in diabetic patients. Sugar alcohols are formed in lens as a consequence of glucose conversion in the sorbitol pathway. The pharmacological modulation of this process by the application of aldose reductase inhibitors are also discussed.