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Case Reports
. 1998 Jul;13(4):693-8.
doi: 10.1002/mds.870130415.

Pallidotomy for generalized dystonia

W G Ondo  1 , J M Desaloms, J Jankovic, R G Grossman
Affiliations
Case Reports

Pallidotomy for generalized dystonia

W G Ondo et al. Mov Disord. 1998 Jul.

Abstract

We systematically evaluated the efficacy of both unilateral and bilateral stereotactic pallidotomy in eight patients with generalized dystonia. Six patients had a marked improvement in dystonic movements and motor function; the other two patients also benefited from the procedure but to a lesser extent. The severity of dystonia was assessed before and after surgery by the Burke-Marsden-Fahn Dystonia Scale (BMFDS), the Unified Dystonia Rating Scale (UDRS), and the Activity of Daily Living Scale (ADL). The BMFDS scores decreased by 59.0%, UDRS by 62.5%, and ADL by 47.8% postoperatively. Adverse events were limited to a transient weakness in one patient. We conclude that pallidotomy is a safe and effective treatment in medically refractory cases of generalized dystonia.

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Comment in

  • Pallidotomy and generalized dystonia.
    Lin JJ, Lin SZ, Chang DC. Lin JJ, et al. Mov Disord. 1999 Nov;14(6):1057-9. doi: 10.1002/1531-8257(199911)14:6<1057::aid-mds1034>3.0.co;2-1. Mov Disord. 1999. PMID: 10584696 No abstract available.

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