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. 1998 Aug;9(8):1961-8.

doi: 10.1091/mbc.9.8.1961.

The membrane-based mechanism of cell motility in cochlear outer hair cells

G I Frolenkov¹, M Atzori, F Kalinec, F Mammano, B Kachar

Affiliations

Affiliation

¹ Section on Structural Cell Biology, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland 20852-3320, USA.

PMID: 9693359
PMCID: PMC25447
DOI: 10.1091/mbc.9.8.1961

Free PMC article

The membrane-based mechanism of cell motility in cochlear outer hair cells

G I Frolenkov et al. Mol Biol Cell. 1998 Aug.

Free PMC article

. 1998 Aug;9(8):1961-8.

doi: 10.1091/mbc.9.8.1961.

Authors

G I Frolenkov¹, M Atzori, F Kalinec, F Mammano, B Kachar

Affiliation

¹ Section on Structural Cell Biology, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland 20852-3320, USA.

PMID: 9693359
PMCID: PMC25447
DOI: 10.1091/mbc.9.8.1961

No abstract available

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Figures

Figure 1
OHC electromotility in an external electric field.

Figure 2
OHC electromotility in whole-cell patch-clamp conditions.

Figure 3
Bending of the OHC in an external electric field

Figure 4
OHC electromotile force is sufficient to produce movement inside the organ of Corti.

Figure 5
OHC electromotility and intracellular pressure.

Figure 6
Effect of salicylate on the OHC electromotility.

Figure 7
Disruption of the OHC cytoskeleton with diamide does not affect electromotility

Figure 8
Electromotile mechanism requires only plasma membrane integrity.

Figure 9
Schematics of OHC force generation unit.

See this image and copyright information in PMC

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References

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