Minimisation: the platinum standard for trials?. Randomisation doesn't guarantee similarity of groups; minimisation does
- PMID: 9694748
- PMCID: PMC1113668
- DOI: 10.1136/bmj.317.7155.362
Minimisation: the platinum standard for trials?. Randomisation doesn't guarantee similarity of groups; minimisation does
Comment in
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Randomised block design is more powerful than minimisation.BMJ. 1999 Jan 23;318(7178):263-4. doi: 10.1136/bmj.318.7178.263. BMJ. 1999. PMID: 9915749 Free PMC article. No abstract available.
References
-
- Taves DR. Minimization: a new method of assigning patients to treatment and control groups. Clin Pharmacol Therap. 1974;15:443–453. - PubMed
-
- Pocock SJ, Simon R. Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. Biometrics. 1975;31:103–115. - PubMed
-
- Freedman LS, White SJ. On the use of Pocock and Simon’s method for balancing treatment numbers over prognostic factors in the controlled clinical trial. Biometrics. 1976;32:691–694. - PubMed
-
- Kallis P, Tooze JA, Talbot S, Cowans D, Bevan DH, Treasure T. Pre-operative aspirin decreases platelet aggregation and increases post-operative blood loss: a prospective, randomised, placebo controlled, double-blind clinical trial in 100 patients with chronic stable angina. Eur J Cardiothoracic Surg. 1994;8:404–409. - PubMed
-
- Smith RL. Sequential treatment allocation using biased coin designs. J Roy Statist Soc B. 1984;46:519–543.
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