[The molecular biology diagnosis of neoplastic blood diseases]
- PMID: 9695255
[The molecular biology diagnosis of neoplastic blood diseases]
Abstract
Molecular-biological approaches was applied for detection of Philadelphia chromosome in patients with chronic myeloid and acute lymphoblastic leukemias. It includes bcr-genomic probes and polymerase chain reaction with specific bcr/abl primers. The latter is more preferable for clinic use. Different diagnostic methods are compared and leukemias etiology problems are discussed.
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