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Review
. 1998 Jun;20(6):480-7.
doi: 10.1002/(SICI)1521-1878(199806)20:6<480::AID-BIES6>3.0.CO;2-Q.

Gene clusters and polycistronic transcription in eukaryotes

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Review

Gene clusters and polycistronic transcription in eukaryotes

T Blumenthal. Bioessays. 1998 Jun.

Abstract

Sometimes genes are arranged nonrandomly on the chromosomes of eukaryotes. This review considers instances of gene clusters in which two genes or more are expressed from a single promoter. This includes cases in which a polycistronic pre-mRNA is processed to make monocistronic mRNAs in nematodes, as well as isolated examples of polycistronic mRNAs found in mammals, flies, and perhaps plants.

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