Comment
doi: 10.1038/1354.
Satisfying turns in folding transitions
- PMID: 9699621
- DOI: 10.1038/1354
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Comment
Satisfying turns in folding transitions
Nat Struct Biol.
1998 Aug.
Abstract
Protein engineering studies show that conformations in the folding transition state ensemble can be structurally polarized. In two SH3 beta-sheet domains, the formation of hydrophobic contacts goes hand in hand with the formation of the solvated distal loop beta-turn, while large parts of the molecule remain unstructured in the ensemble.
Comment on
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Important role of hydrogen bonds in the structurally polarized transition state for folding of the src SH3 domain.Nat Struct Biol. 1998 Aug;5(8):714-20. doi: 10.1038/1412. Nat Struct Biol. 1998. PMID: 9699636
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Obligatory steps in protein folding and the conformational diversity of the transition state.Nat Struct Biol. 1998 Aug;5(8):721-9. doi: 10.1038/1418. Nat Struct Biol. 1998. PMID: 9699637