RNA-binding proteins tamed
- PMID: 9699622
- DOI: 10.1038/1356
RNA-binding proteins tamed
Abstract
Novel RNA-binding proteins with customized specificities can be isolated by genetic selection from combinatorial libraries. Such proteins have great potential as agents for targeted manipulation of gene expression.
Comment on
-
Specific RNA binding proteins constructed from zinc fingers.Nat Struct Biol. 1998 Jul;5(7):543-6. doi: 10.1038/794. Nat Struct Biol. 1998. PMID: 9665165
Similar articles
-
In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation.J Mol Biol. 2004 Aug 13;341(3):635-49. doi: 10.1016/j.jmb.2004.06.030. J Mol Biol. 2004. PMID: 15288776
-
Discovery of active proteins directly from combinatorial randomized protein libraries without display, purification or sequencing: identification of novel zinc finger proteins.Nucleic Acids Res. 2005 Feb 18;33(3):e32. doi: 10.1093/nar/gni031. Nucleic Acids Res. 2005. PMID: 15722478 Free PMC article.
-
Comparison of mRNA-display-based selections using synthetic peptide and natural protein libraries.Biochemistry. 2007 Sep 4;46(35):10102-12. doi: 10.1021/bi700220x. Epub 2007 Aug 9. Biochemistry. 2007. PMID: 17685586
-
Sequence and structure space of RNA-binding peptides.Biopolymers. 2003 Sep;70(1):80-5. doi: 10.1002/bip.10429. Biopolymers. 2003. PMID: 12925994 Review.
-
[Screening for novel RNA-binding peptides from combinatorial libraries].Tanpakushitsu Kakusan Koso. 1999 Sep;44(11):1572-83. Tanpakushitsu Kakusan Koso. 1999. PMID: 10483299 Review. Japanese. No abstract available.
Cited by
-
A new hydrogen-bonding potential for the design of protein-RNA interactions predicts specific contacts and discriminates decoys.Nucleic Acids Res. 2004 Sep 30;32(17):5147-62. doi: 10.1093/nar/gkh785. Print 2004. Nucleic Acids Res. 2004. PMID: 15459285 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources