Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1998 Aug 10;142(3):609-12.
doi: 10.1083/jcb.142.3.609.

Spatial regulation of exocytosis: lessons from yeast

F P Finger  1 , P Novick
Affiliations
Review

Spatial regulation of exocytosis: lessons from yeast

F P Finger et al. J Cell Biol. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Model for establishment of a polarized secretory pathway. Sec3p localizes to a domain of the plasma membrane independent of the actin cytoskeleton, defining the site of exocytosis. Vesicles are transported to the correct region of the cell on actin cables, perhaps using Myo2p as the motor. The activation of Sec4p, on vesicles, by Sec2p allows polarized delivery of vesicles. Sec15p may dock the correctly targeted vesicles at the docking/fusion site via interactions with other components of the Sec3/5/6/8/10/15–Exo70p complex. Y shapes, v-SNAREs on the vesicles; crosses, t-SNAREs on the plasma membrane.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Amatruda JF, Gattermeir DJ, Karpova TS, Cooper JA. Effects of null mutations and overexpression of capping protein on morphogenesis, actin distribution, and polarized secretion in yeast. J Cell Biol. 1992;119:1151–1162. - PMC - PubMed
    1. Amberg DC, Zahner JE, Mulholland JW, Pringle JR, Botstein D. Aip3/Bud6p, a yeast actin-interacting protein that is involved in morphogenesis and the selection of bipolar bud sites. Mol Biol Cell. 1997;8:729–753. - PMC - PubMed
    1. Ayscough KR, Stryker J, Pokala N, Sanders M, Crews P, Drubin DG. High rates of actin filament turnover in budding yeast and roles for actin in establishment and maintenance of cell polarity revealed using the actin inhibitor latrunculin-A. J Cell Biol. 1997;137:399–416. - PMC - PubMed
    1. Bi G-Q, Morris RL, Liao G, Alderton JM, Scholey JM, Steinhardt RA. Kinesin- and myosin-driven steps of vesicle recruitment for Ca2+-regulated exocytosis. J Cell Biol. 1997;138:999–1008. - PMC - PubMed
    1. Botstein, D., D. Amberg, J. Mulholland, T. Huffaker, A. Adams, D. Drubin and T. Stearns. The Yeast Cytoskeleton. In The Molecular and Cellular Biology of the Yeast Saccharomyces. J.R. Broach, J.R. Pringle, and E.W. Jones, editors. 1997. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 1–90.

MeSH terms