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Review
. 1998 Aug 10;142(3):609-12.
doi: 10.1083/jcb.142.3.609.

Spatial regulation of exocytosis: lessons from yeast

F P Finger  1 , P Novick
Affiliations
Review

Spatial regulation of exocytosis: lessons from yeast

F P Finger et al. J Cell Biol. .
No abstract available

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Figures

Figure 1
Figure 1
Model for establishment of a polarized secretory pathway. Sec3p localizes to a domain of the plasma membrane independent of the actin cytoskeleton, defining the site of exocytosis. Vesicles are transported to the correct region of the cell on actin cables, perhaps using Myo2p as the motor. The activation of Sec4p, on vesicles, by Sec2p allows polarized delivery of vesicles. Sec15p may dock the correctly targeted vesicles at the docking/fusion site via interactions with other components of the Sec3/5/6/8/10/15–Exo70p complex. Y shapes, v-SNAREs on the vesicles; crosses, t-SNAREs on the plasma membrane.
See this image and copyright information in PMC

References

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MeSH terms