Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1998 Jul;2(1):141-7.
doi: 10.1016/s1097-2765(00)80123-9.

Function of hexameric RNA in packaging of bacteriophage phi 29 DNA in vitro

F Zhang  1 , S Lemieux, X Wu, D St-Arnaud, C T McMurray, F Major, D Anderson
Affiliations
Free article
Comparative Study

Function of hexameric RNA in packaging of bacteriophage phi 29 DNA in vitro

F Zhang et al. Mol Cell. 1998 Jul.
Free article

Erratum in

  • Mol Cell 1998 Sep;2(3):405

Abstract

A cyclic hexamer of the 120-base prohead RNA (pRNA) is needed for efficient in vitro packaging of the B. subtilis bacteriophage phi 29 genome. This capacity of pRNA to form higher multimers by intermolecular base pairing of identical subunits represents a new RNA structural motif. Dimers of pRNA are likely intermediates in formation of the cyclic hexamer. A three-dimensional model of the pRNA hexamer is presented.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources