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. 1976 Sep;6(5):613-7.
doi: 10.1007/BF01971579.

Pertussis vaccine oedema: an experimental model for the action of penicillamine-like drugs

E Arrigoni-Martelli, E Bramm, E C Huskisson, D A Willoughby, P A Dieppe

Pertussis vaccine oedema: an experimental model for the action of penicillamine-like drugs

E Arrigoni-Martelli et al. Agents Actions. 1976 Sep.

Abstract

A delayed hypersensitivity response was induced in the rat paw using pertussis vaccine. Oedema was measured after the challenging injection. D-penicillamine and levamisole enhanced the response, while indomethacin suppressed it. This model is useful to distinguish the effects of anti-inflammatory drugs from those like D-Penicillamine which have a specific activity in rheumatoid arthritis.

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References

    1. Agents Actions. 1976 Sep;6(5):618-21 - PubMed
    1. Postgrad Med J. 1974 Aug;50 Suppl 2:59-61 - PubMed
    1. Agents Actions. 1975 Aug;5(3):264-7 - PubMed
    1. J Pathol Bacteriol. 1966 Jul;92(1):139-50 - PubMed
    1. Arzneimittelforschung. 1975 Apr;25(4):600-3 - PubMed

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