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. 1976 Oct;66(4):753-9.
doi: 10.1093/ajcp/66.4.753.

Mapping of several abnormal hemoglobins by horizontal polyacrylamide gel isoelectric focusing

Mapping of several abnormal hemoglobins by horizontal polyacrylamide gel isoelectric focusing

M Monte et al. Am J Clin Pathol. 1976 Oct.

Abstract

The relative mobilities of serveral human hemoglobin variants were studied by use of an isoelectric focusing method in a thin-layer horizontal polyacrylamide gel. The technic is described in detail and a preliminary mapping of these variants is presented. It appears that thin-layer gel isoelectric focusing is a method that is rapid, highly reproducible and easily applicable in laboratories concerned with the study of hemoglobinopathies.

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