Cell death: shadow baxing
- PMID: 9705928
- DOI: 10.1016/s0960-9822(07)00339-9
Cell death: shadow baxing
Abstract
Bcl-2, one of a family of key regulators of apoptosis, was the first cell-death machinery component to be identified, but how the family functions is still not clear. Mammalian Bax, a pro-apoptotic family member, can cause yeast cells to die, and two recent yeast genetic screens shed light on how Bax might function.
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