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Review
. 1998 Jul 16;8(15):R528-31.
doi: 10.1016/s0960-9822(07)00339-9.

Cell death: shadow baxing

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Free article
Review

Cell death: shadow baxing

J Silke et al. Curr Biol. .
Free article

Abstract

Bcl-2, one of a family of key regulators of apoptosis, was the first cell-death machinery component to be identified, but how the family functions is still not clear. Mammalian Bax, a pro-apoptotic family member, can cause yeast cells to die, and two recent yeast genetic screens shed light on how Bax might function.

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