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. 1998 Jan-Mar;17(1-3):301-8.
doi: 10.1080/07328319808005178.

Two hydrolase resistant analogues of diadenosine 5',5"'-P1,P3-triphosphate for studies with Fhit, the human fragile histidine triad protein

G M Blackburn  1 , X Liu, A Rösler, C Brenner
Affiliations

Two hydrolase resistant analogues of diadenosine 5',5"'-P1,P3-triphosphate for studies with Fhit, the human fragile histidine triad protein

G M Blackburn et al. Nucleosides Nucleotides. 1998 Jan-Mar.

Abstract

The design and synthesis of analogues of diadenosine 5',5"'-P1,P3-triphosphate that are resistant to pyrophosphate hydrolysis is described in relation to their rôle in signalling and tumorigenesis involving the Fhit protein, the human fragile histidine triad protein, which is a novel Ap3A binding/cleaving protein.

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