doi: 10.1002/eji.1830080407.
Antibody against rabbit immunoglobulin VH and L chain allotype determinants in heterologous anti-Ig antisera
- PMID: 97086
- DOI: 10.1002/eji.1830080407
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Antibody against rabbit immunoglobulin VH and L chain allotype determinants in heterologous anti-Ig antisera
Eur J Immunol.
1978 Apr.
Abstract
Heterologous anti-rabbit IgG antisera have been examined by radioimmunoassay for the occurrence of anti-VH antibody. Most of the sera contained antibody specific for VH allotype determinants (Aal). The antisera contained as much or more anti-al antibody as estimated in conventional alloantisera. It has further been shown that the anti-L chain antibody in all these sera was specific for L chain allotype determinants. Antibody against H chain-dependent L chain conformational determinants or cross-reacting determinants in CHlgamma and CHlalpha could not be demonstrated.
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